The pharmacotherapy of depressive illness in adolescence: II. Effects of lithium augmentation in nonresponders to imipramine.

@article{Strober1992ThePO,
  title={The pharmacotherapy of depressive illness in adolescence: II. Effects of lithium augmentation in nonresponders to imipramine.},
  author={Michael Strober and Roberta Freeman and Justin F Rigali and S Schmidt and Robert P. Diamond},
  journal={Journal of the American Academy of Child and Adolescent Psychiatry},
  year={1992},
  volume={31 1},
  pages={16-20}
}
The antidepressant value of lithium augmentation was assessed in a 3-week open trial involving 24 adolescents who remained highly depressed after 6 weeks of treatment with imipramine hydrochloride. Two patients responded dramatically during the first week, with an additional eight patients showing partial improvement during the 3-week trial. The overall… CONTINUE READING