The pharmacology of the neurochemical transmission in the midbrain raphe nuclei of the rat.

@article{Hrsing2006ThePO,
  title={The pharmacology of the neurochemical transmission in the midbrain raphe nuclei of the rat.},
  author={L{\'a}szl{\'o} G{\'a}bor H{\'a}rsing},
  journal={Current neuropharmacology},
  year={2006},
  volume={4 4},
  pages={313-39}
}
Midbrain slices containing the dorsal and medial raphe nuclei were prepared from rat brain, loaded with [(3)H]serotonin ([(3)H]5-HT), superfused and the release of [(3)H]5-HT was determined at rest and in response to electrical stimulation. Compartmental analysis of [(3)H]5-HT taken up by raphe tissue indicated various pools where the neurotransmitter release may originate from these stores differed both in size and rate constant. 5-HT release originates not only from vesicles but also from… CONTINUE READING
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