The pharmacology of the benzodiazepine site of the GABA-A receptor is dependent on the type of gamma-subunit present.

The pharmacology of native and recombinant GABA-A receptors containing either gamma1, gamma2 or gamma3 subunits has been investigated. The pharmacology of native receptors has been investigated by immunoprecipitating receptors from solubilised preparations of rat brain with antisera specific for individual gamma-subunits and analysing their radioligand… CONTINUE READING