Corpus ID: 36950795

The pharmacology of benoxaprofen with particular to effects on lipoxygenase product formation.

@article{Dawson1982ThePO,
  title={The pharmacology of benoxaprofen with particular to effects on lipoxygenase product formation.},
  author={William Dawson and John R. Boot and J Harvey and J. R. L. Walker},
  journal={European journal of rheumatology and inflammation},
  year={1982},
  volume={5 2},
  pages={
          61-8
        }
}
Benoxaprofen has three pharmacological activities which may relate to its clinical activity profile. The most important of these for anti-inflammatory therapy is the regulation of directional monocyte movement in response to a stimulus but the inhibitory activity against lipoxygenase may be of considerable relevance in the treatment of asthma. The relatively weak inhibitory action on prostaglandin synthetase probably confers clinical benefit with a reduced potential to cause severe gastric side… Expand
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