The pharmacology and toxicology of the interferons: an overview.

  title={The pharmacology and toxicology of the interferons: an overview.},
  author={G J Mannering and Laurel B. Deloria},
  journal={Annual review of pharmacology and toxicology},
Interferon was discovered three decades ago. The next 20 or more years of research were directed largely toward an understanding of its antiviral activity. The persistent short supply of interferon hampered progress, and the impure preparations available throughout these years clouded interpretation of results. Many of the experiments and clinical studies that interferonologists had dreamed of for 20 or more years became realities when modern technology provided quantities of pure interferon… CONTINUE READING


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