The pharmacological treatment of acquired nystagmus

@article{Mehta2012ThePT,
  title={The pharmacological treatment of acquired nystagmus},
  author={Arpan R. Mehta and Christopher Kennard},
  journal={Practical Neurology},
  year={2012},
  volume={12},
  pages={147 - 153}
}
We review the latest literature on the neuropharmacological treatments for acquired nystagmus. Nystagmus may have a significantly impact on health, yet there is little scientific evidence on which to make firm recommendations for treatment. Acquired pendular nystagmus may respond to gabapentin or memantine; downbeat and upbeat nystagmus to aminopyridines; and periodic alternating nystagmus to baclofen. To improve treatment we need multi-centre, randomised controlled trials using standardised… Expand
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Mechanisms that cause nystagmus are better understood in some forms, such as acquired periodic alternating nyStagmus, than in others, for example acquired pendular nySTAGmus, for which there is limited knowledge. Expand
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It was concluded that memantine is a safe treatment option for APN, and all 11 patients with fixational pendular nystagmus who were given memantine, a glutamate antagonist, experienced complete cessation of the nyStagmus. Expand
Crossover trial of gabapentin and memantine as treatment for acquired nystagmus
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Both gabapentin and memantine should be considered as treatment for acquired forms of nystagmus, and each patient improved with 1 or both drugs. Expand
Muscarinic antagonists in the treatment of acquired pendular and downbeat nystagmus: A double‐blind, randomized trial of three intravenous drugs
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Visual acuity improved only with scopolamine; motion discrimination and oscillopsia improved significantly with scolinamine and benztropine. Expand
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