Corpus ID: 30160846

The pharmacological classification of practolol and chloropractolol.

@article{Kenakin1978ThePC,
  title={The pharmacological classification of practolol and chloropractolol.},
  author={Terry Kenakin and James W. Black},
  journal={Molecular pharmacology},
  year={1978},
  volume={14 4},
  pages={
          607-23
        }
}
The classification of beta adrenoceptor subtypes has apparently received substantial confirmation from the cardioselective properties of practolol, so-called beta 1 receptor blockade. This interpretation assumes that practolol has no relevant pharmacological properties other than beta receptor antagonism; the present report challenges that assumption. Practolol was studied to elucidate the reported alkylating properties of chloropractolol; although no evidence of alkylation was found, the… Expand
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