The pharmacologic treatment of depression: is gender a critical factor?

@article{Yonkers2002ThePT,
  title={The pharmacologic treatment of depression: is gender a critical factor?},
  author={Kimberly Ann Yonkers and Olga Brawman-Mintzer},
  journal={The Journal of clinical psychiatry},
  year={2002},
  volume={63 7},
  pages={610-5}
}
BACKGROUND In the medical literature, there is a lack of sex-specific information regarding the efficacy, metabolism, and side effects associated with psychopharmacologic treatment. In part, this lack results from the historic underinclusion of women in clinical trials during early drug development, but it also occurs because investigators of treatment and metabolic studies do not routinely analyze results according to sex. In 1993, the U.S. Food and Drug Administration (FDA) announced changes… CONTINUE READING

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