The pharmacokinetics of tacrolimus after first and repeated dosing with 0.03% ointment in infants with atopic dermatitis.

Abstract

BACKGROUND In adults and children aged > 2 years, systemic absorption of tacrolimus from tacrolimus ointment is very low. In this study, the pharmacokinetics of tacrolimus 0.03% ointment were investigated in infants aged 3-24 months. METHODS The pharmacokinetics of tacrolimus after first and repeated topical application of tacrolimus 0.03% ointment were… (More)
DOI: 10.1111/j.1365-4632.2009.03853.x

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