• DOI:10.1111/J.1365-2125.1993.TB04191.X
Corpus ID: 36326479

The pharmacokinetics of remoxipride and metabolites in patients with various degrees of renal function.

@article{MovinOsswald1993ThePO,
  title={The pharmacokinetics of remoxipride and metabolites in patients with various degrees of renal function.},
  author={G. Movin-Osswald and J. Boelaert and M. Hammarlund-Udenaes and L. Nilsson},
  journal={British journal of clinical pharmacology},
  year={1993},
  volume={35 6},
  pages={
          615-22
        }
}

G. Movin-Osswald, J. Boelaert, +1 author L. Nilsson

Published 1993

Medicine

British journal of clinical pharmacology

1. The pharmacokinetics of remoxipride, a new neuroleptic, were investigated in an open study with three parallel groups. Twenty-one patients with severely impaired (ClCr < 25 ml min-1), moderately impaired (ClCr 25-50 ml min-1) and normal (ClCr > 65 ml min-1) renal function were evaluated. A single oral dose of remoxipride hydrochloride 100 mg was administered, and blood and urine were collected over 48 h. Concentrations of remoxipride and metabolites were measured by h.p.l.c. 2. In patients… CONTINUE READING

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