The pharmacokinetics of morphine and morphine glucuronides in kidney failure

@article{Osborne1993ThePO,
  title={The pharmacokinetics of morphine and morphine glucuronides in kidney failure},
  author={R. Osborne and S. Joel and K. Grebenik and D. Trew and M. Slevin},
  journal={Clinical Pharmacology & Therapeutics},
  year={1993},
  volume={54}
}
The pharmacokinetics of morphine and its glucuronide metabolites were investigated in three groups of patients with kidney failure (nondialyzed, receiving dialysis, and transplantation) and compared with a group of normal healthy volunteers. Patients in all three renal groups were undergoing surgical procedures (nondialyzed group undergoing arteriovenous fistula formation, dialysis group undergoing placement of a peritoneal dialysis catheter, and the transplant group undergoing live donor… Expand
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