The pharmacokinetics, tissue distribution, and biotransformation of a new class of antitumor agents: mitonafide and pinafide

Abstract

The pharmacokinetics, biotransformation, protein binding and tissue distribution of mitonafide and pinafide were studied after single i.v. and oral administration of each drug (20 mg/Kg) in female rats. In pregnant rats a study of cross placental-barrier after i.v. administration of the two drugs was also performed. The drugs were absorbed fairly rapidly… (More)
DOI: 10.1007/BF03189110

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@article{Cid1986ThePT, title={The pharmacokinetics, tissue distribution, and biotransformation of a new class of antitumor agents: mitonafide and pinafide}, author={P. Rivera Cid and Emmanuel Fernandez and Fred Martin and Miguel F Bra{\~n}a}, journal={European Journal of Drug Metabolism and Pharmacokinetics}, year={1986}, volume={11}, pages={255-267} }