The pharmacodynamic effect of omeprazole 10 mg and 20 mg once daily in patients with nonerosive reflux disease in Japan

@article{Kinoshita2006ThePE,
  title={The pharmacodynamic effect of omeprazole 10 mg and 20 mg once daily in patients with nonerosive reflux disease in Japan},
  author={Yoshikazu Kinoshita and Takeaki Kobayashi and Mototsugu Kato and Kan Asahina and Ken Haruma and Tomohiko Shimatani and Shuji Inoue and Teppei Kabemura and Susumu Kurosawa and Hajime Kuwayama and Kiyoshi Ashida and Michiaki Hirayama and Satoshi Kiyama and Munemitsu Yamamoto and Junichi Suzuki and Hiroyuki Suzuki and Katsuhiko Matsumoto and Masaru Aoshima},
  journal={Journal of Gastroenterology},
  year={2006},
  volume={41},
  pages={554-561}
}
To evaluate the pharmacodynamic effect, efficacy, and safety of omeprazole 10 mg and 20 mg once daily in patients with nonerosive reflux disease (NERD) in Japan. A total of 37 patients were randomized to omeprazole 10 mg or omeprazole 20 mg once daily for 4 weeks. Eligible patients had a history of moderate-to-severe heartburn for 2 days or more per week during the last 1 month or longer prior to the study screening, grade M or grade N on Hoshihara's modification of the Los Angeles… CONTINUE READING