The pha-4 gene is required to generate the pharyngeal primordium of Caenorhabditis elegans.

@article{Mango1994ThePG,
  title={The pha-4 gene is required to generate the pharyngeal primordium of Caenorhabditis elegans.},
  author={Susan E Mango and Eric J Lambie and Judith Kimble},
  journal={Development},
  year={1994},
  volume={120 10},
  pages={3019-31}
}
In the 4-cell Caenorhabditis elegans embryo, two blastomeres are destined to generate pharyngeal cells, each by a distinct developmental strategy: one pathway is inductive, while the other is autonomous. Here, we identify the pha-4 locus. In animals lacking pha-4 activity, an early step in pharyngeal organogenesis is blocked: no pharyngeal primordium is formed and differentiated pharyngeal cells are absent. Most other tissues are generated normally in pha-4 mutants, including cells related to… CONTINUE READING
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