The persistence of the placebo response in antidepressant clinical trials.

@article{Khan2008ThePO,
  title={The persistence of the placebo response in antidepressant clinical trials.},
  author={Arif Khan and Nick Redding and Walter Armin Brown},
  journal={Journal of psychiatric research},
  year={2008},
  volume={42 10},
  pages={
          791-6
        }
}
Our objective was to assess the persistence of the placebo response during at least 12 weeks of continued placebo administration in depressed patients who have responded to 6-8 weeks of acute placebo treatment. We identified 8 placebo-controlled antidepressant trials with a total of 3,063 depressed patients in which, after acute phase placebo treatment, placebo was continued for more than 12 weeks. The number of patients entering the continuation phase and percentages relapsing during this… CONTINUE READING

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