The persistence of anti-hepatitis B surface antibodies to three years of age: is a hepatitis B vaccine booster required?

@article{Gunn1993ThePO,
  title={The persistence of anti-hepatitis B surface antibodies to three years of age: is a hepatitis B vaccine booster required?},
  author={Tania R. Gunn and D. Graeme Woodfield},
  journal={The New Zealand medical journal},
  year={1993},
  volume={106 968},
  pages={499-501}
}
AIMS To evaluate the persistence of hepatitis B surface antibodies (anti-HBs) after immunisation in early infancy. METHODS The infants were born to low risk European mothers negative for hepatitis B surface antigen (HBsAg). All the children had received 3 doses of 20 micrograms of recombinant DNA hepatitis B vaccine. RESULTS One month after the third dose all 92 infants were seropositive. The GMT was 1190 mIU/mL and all but one infant had seroprotective titres above 10 mIU/mL. Three years… CONTINUE READING
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