The peripheral-type benzodiazepine receptor: a protein of mitochondrial outer membranes utilizing porphyrins as endogenous ligands.

@article{Snyder1987ThePB,
  title={The peripheral-type benzodiazepine receptor: a protein of mitochondrial outer membranes utilizing porphyrins as endogenous ligands.},
  author={Solomon H Snyder and Ajay Verma and Rosario Rich Trifiletti},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={1987},
  volume={1 4},
  pages={282-8}
}
The peripheral-type benzodiazepine receptor is a site identified by its nanomolar affinity for [3H]diazepam, similar to the affinity of diazepam for the central-type benzodiazepine receptor in the brain. The peripheral-type benzodiazepine receptor occurs in many peripheral tissues but has discrete localizations as indicated by autoradiographic studies showing uniquely high densities of the receptors in the adrenal cortex and in Leydig cells of the testes. Subcellular localization studies reveal… CONTINUE READING
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