The perioperative period is an underutilized window of therapeutic opportunity in patients with colorectal cancer.


OBJECTIVE In this review, we address the underlying mechanisms by which surgery augments metastases outgrowth and how these insights can be used to develop perioperative therapeutic strategies for prevention of tumor recurrence. SUMMARY BACKGROUND DATA Surgical removal of the primary tumor provides the best chance of long-term disease-free survival for… (More)
DOI: 10.1097/SLA.0b013e3181a3ddbd

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