The perceived effects of smoked cannabis on patients with multiple sclerosis.

  title={The perceived effects of smoked cannabis on patients with multiple sclerosis.},
  author={Paul F. Consroe and Richard E. Musty and Jennifer Rein and Wanda Kaye Tillery and Roger G. Pertwee},
  journal={European neurology},
  volume={38 1},
Fifty-three UK and 59 USA people with multiple sclerosis (MS) answered anonymously the first questionnaire on cannabis use and MS. From 97 to 30% of the subjects reported cannabis improved (in descending rank order): spasticity, chronic pain of extremities, acute paroxysmal phenomenon, tremor, emotional dysfunction, anorexia/weight loss, fatigue states, double vision, sexual dysfunction, bowel and bladder dysfunctions, vision dimness, dysfunctions of walking and balance, and memory loss. The MS… 
Patterns of cannabis use among patients with multiple sclerosis
The symptoms reported by medical cannabis users to be most effectively relieved were stress, sleep, mood, stiffness/spasm, and pain.
Effects of cannabis on cognitive function in patients with multiple sclerosis
This cross-sectional study provides empirical evidence that prolonged use of inhaled or ingested street cannabis in patients with MS is associated with poorer performance on cognitive domains commonly affected in this population.
Cannabis use in patients with multiple sclerosis
A large proportion of MS patients had tried cannabis for symptom control, however current use was small and a subgroup with greater disability appears to derive some symptomatic benefit.
Cannabis in Multiple Sclerosis: Women's Health Concerns
Large-scale clinical trials are underway to answer questions concerning the efficacy and safety of cannabis in patients with MS and additional studies in female MS patients will be needed to address issues such as gender-specific actions on symptoms such as pain and autonomic dysfunction.
Psychopathological and Cognitive Effects of Therapeutic Cannabinoids in Multiple Sclerosis: A Double-Blind, Placebo Controlled, Crossover Study
Cannabinoid treatment did not induce psychopathology and did not impair cognition in cannabis-naïve patients with MS, but the positive correlation between blood levels of &Dgr;-9-tetrahydrocannabinol and psychopathological scores suggests that at dosages higher than those used in therapeutic settings, interpersonal sensitivity, aggressiveness, and paranoiac features might arise.
The effect of cannabis on tremor in patients with multiple sclerosis
A randomized double-blind placebo-controlled crossover trial to examine the effect of oral cannador (cannabis extract) on 14 patients with MS with upper limb tremors found that cannabis extract does not produce a functionally significant improvement in MS-associated tremor.
Cannabis Use in Multiple Sclerosis: Excited Interest
  • J. Killestein, C. Polman
  • Psychology, Medicine
    Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
  • 2003
The questionnaire study by Page, et al is timely and represents the best designed questionnaire study on cannabis use in MS so far, but the small number of patients using cannabis medicinally on a regular basis is slightly limiting the possibility to draw firm conclusions.