The pepper's natural ingredient capsaicin induces autophagy blockage in prostate cancer cells

@inproceedings{RamosTorres2016ThePN,
  title={The pepper's natural ingredient capsaicin induces autophagy blockage in prostate cancer cells},
  author={{\'A}gata Ramos-Torres and Alicia Bort and Cecilia Morell and Nieves Rodr{\'i}guez-Henche and In{\'e}s D{\'i}az-Laviada},
  booktitle={Oncotarget},
  year={2016}
}
Capsaicin, the pungent ingredient of red hot chili peepers, has been shown to have anti-cancer activities in several cancer cells, including prostate cancer. Several molecular mechanisms have been proposed on its chemopreventive action, including ceramide accumulation, endoplasmic reticulum stress induction and NFκB inhibition. However, the precise mechanisms by which capsaicin exerts its anti-proliferative effect in prostate cancer cells remain questionable. Herein, we have tested the… CONTINUE READING
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