The penetration of antibiotics into human pancreas

  title={The penetration of antibiotics into human pancreas},
  author={Priv. Doz. Dr. med. M. B{\"u}chler and Helmut Friess and Prof. Dr. med. R. Bittner and Prof. Dr. med. H. G. Beger and Priv. Doz. Dr. med. P. Malfertheiner and Prof. Dr. med. E. Vanek and Dr. med. P. Schlegel},
In order to analyse the penetration of two antibiotics (mezlocillin and metronidazole) which cover the spectrum of microorganisms involved in pancreatic infection, we determined their concentration in pancreatic tissue, juice and cyst fluid in 16 patients undergoing pancreatic surgery. In addition, the external pancreatic fistula fluid of one patient was analysed for antibiotic concentration and bacterial counts during a seven-day treatment with mezlocillin, metronidazole and netilmicin (i.v… CONTINUE READING


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