The pel1 mutant of Saccharomyces cerevisiae is deficient in cardiolipin and does not survive the disruption of the CHO1 gene encoding phosphatidylserine synthase.

@article{Janitor1996ThePM,
  title={The pel1 mutant of Saccharomyces cerevisiae is deficient in cardiolipin and does not survive the disruption of the CHO1 gene encoding phosphatidylserine synthase.},
  author={Martin Janitor and Margita Obernauerov{\'a} and Sepp D. Kohlwein and J{\'u}lius {\vS}ub{\'i}k},
  journal={FEMS microbiology letters},
  year={1996},
  volume={140 1},
  pages={43-7}
}
Cells of the pel1 mutant of Saccharomyces cerevisiae were found to contain an extremely low content of cardiolipin, a decreased level of phosphatidylcholine and an increased level of phosphatidylinositol. Disruption of the PEL1 gene in cells containing a null mutation in the CHO1 gene was lethal. Despite its putative functional homology with CHO1, the overexpression of the PEL1 gene in the cho1 null mutant did not restore the wild-type properties of the transformed cells and failed to stimulate… CONTINUE READING

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The pel1 mutant of Saccharomyces cerevisiae is deficient in cardiolipin and does not survive the disruption of the CHO1 gene encoding phosphatidylserine synthase .
The pel1 mutant of Saccharomyces cerevisiae is deficient in cardiolipin and does not survive the disruption of the CHO1 gene encoding phosphatidylserine synthase .
Cells of the pel1 mutant of Saccharomyces cerevisiae were found to contain an extremely low content of cardiolipin , a decreased level of phosphatidylcholine and an increased level of phosphatidylinositol .
Cells of the pel1 mutant of Saccharomyces cerevisiae were found to contain an extremely low content of cardiolipin , a decreased level of phosphatidylcholine and an increased level of phosphatidylinositol .
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