The pedunculopontine nucleus area: critical evaluation of interspecies differences relevant for its use as a target for deep brain stimulation.

@article{Alam2011ThePN,
  title={The pedunculopontine nucleus area: critical evaluation of interspecies differences relevant for its use as a target for deep brain stimulation.},
  author={Mesbah Alam and Kerstin Schwabe and Joachim K. Krauss},
  journal={Brain : a journal of neurology},
  year={2011},
  volume={134 Pt 1},
  pages={11-23}
}
Recently, the pedunculopontine nucleus has been highlighted as a target for deep brain stimulation for the treatment of freezing of postural instability and gait disorders in Parkinson's disease and progressive supranuclear palsy. There is great controversy, however, as to the exact location of the optimal site for stimulation. In this review, we give an overview of anatomy and connectivity of the pedunculopontine nucleus area in rats, cats, non-human primates and humans. Additionally, we… CONTINUE READING
Highly Influential
This paper has highly influenced 14 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 59 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 129 references

Cholinergic neurons in the pedunculopontine tegmental nucleus are involved in the mediation of prepulse The pedunculopontine nucleus area : interspecies differences and deep brain stimulation

M Koch, M Kungel, H Herbert
Brain • 2011

Effect of globus pallidus internus and/or pedunculopontine nucleus DBS on posture and gait ignition in advanced Parkinson’s disease.? (Poster-814)

C Schrader, H Capelle, +3 authors F. Seehaus
Movement Disord 2010; • 2010

Similar Papers

Loading similar papers…