The pedunculopontine nucleus

  title={The pedunculopontine nucleus},
  author={Edgar Garcia-Rill},
  journal={Progress in Neurobiology},
  • E. Garcia-Rill
  • Published 31 December 1991
  • Biology
  • Progress in Neurobiology

The pedunculopontine tegmental nucleus and experimental parkinsonism

A functional model of basal ganglia circuitry is proposed in which the role of the Ppn is emphasized and the underlying mechanisms of parkinsonism are discussed.

Neuronal Activity of Monkey Pedunculopontine Tegmental Nucleus Area II

By this pallidotomy, a muscle rigidity and akinesia can be effectively abolished and a gait disturbance and balance problems could also be improved.

The Pedunculopontine Nucleus

The synthesis of the literature suggests that it is no longer sufficient to view PPN neurons as playing roles in only one of two distinct effector systems, namely the RAS and MLR, but that individual PPN neuron are ideally suited to play central roles in both systems.

Efferent connections of the internal globus pallidus in the squirrel monkey: II. topography and synaptic organization of pallidal efferents to the pedunculopontine nucleus

The first objective of the present study was to verify whether projections from regions of the internal pallidum (GPi) that receive inputs from different functional areas of the striatum remain

Cholinergic neurons in the pedunculopontine tegmental nucleus are involved in the mediation of prepulse inhibition of the acoustic startle response in the rat

The present data indicate that the pathway mediating PPI impinges upon the primary acoustic startle circuit through an inhibitory cholinergic projection from the PPTg to the PnC.

THE PEDUNCULOPONTINE NUCLEUS : Towards a Functional Integration with the Basal Ganglia

The anatomical, physiological and behavioural evidence suggests that the PPN and the basal ganglia could be considered as part of the same functional circuit, and the aim of this chapter is to present some of the information supporting this notion.

Pedunculo-pontine control of visually guided saccades.

Activity in mouse pedunculopontine tegmental nucleus reflects action and outcome in a decision-making task.

The results suggest that the pedunculopontine tegmental nucleus should be considered within the network of brain areas responsible for sensorimotor decision making and lay the foundation for future experiments to examine how the PPTg interacts with other regions to control sensory-guided motor output.



Midlatency auditory evoked responses in the human and the cat model.

Findings from the experiments summarized above indicate that the MRL components, Pa and P1, are differentially affected by several functional and parametric variables, suggesting that each of these

Origin of ascending and spinal pathways from the nucleus tegmenti pedunculopontinus in the rat

The distribution and collaterlization of ascending and descending projections from neurons in the nucleus tegmenti pedunculopontinus (PPN) were studied in the rat by using retrograde transport of

Cholinergic vs. noncholinergic efferents from the mesopontine tegmentum to the extrapyramidal motor system nuclei

The rat PPTn is defined as a large‐celled, cholinergic nucleus and a group of smaller, noncholinergic neurons that are medially adjacent to the P PTn is cytologically distinct from this group.

Hippocampal projections and related neural pathways to the midbrain in the cat.

  • W. Nauta
  • Biology
    Brain : a journal of neurology
  • 1958
Recent studies in the rat have confirmed much earlier descriptions of widespread distributions of the fornix system to the diencephalon and the rostral mid-brain regions.

The basal ganglia and the locomotor regions