The peculiar spectrum of beta-thalassemia genes in Tunisia.

  title={The peculiar spectrum of beta-thalassemia genes in Tunisia.},
  author={Jemni Chibani and Michel Vidaud and Philippe Duquesnoy and J L Berge-lefranc and Mario Pirastu and Farielle Ellouze and Jean Rosa and Michel Goossens},
  journal={Human genetics},
  volume={78 2},
We have determined the spectrum of mutations producing beta-thalassemia (beta-thal) in Tunisia by direct DNA analysis using hybridization with allele-specific oligonucleotide probes and restriction endonuclease assay. In all, 34 unrelated beta-thal patients originating from different parts of the country were available for study. The beta-globin gene… CONTINUE READING