The pdr12 ABC transporter is required for the development of weak organic acid resistance in yeast.

@article{Piper1998ThePA,
  title={The pdr12 ABC transporter is required for the development of weak organic acid resistance in yeast.},
  author={Peter W Piper and Y Mah{\'e} and Stephen E. Thompson and Rudy Pandjaitan and Caroline D. Holyoak and Ralf Egner and Marcus Muehlbauer and Peter J Coote and Karl Kuchler},
  journal={The EMBO journal},
  year={1998},
  volume={17 15},
  pages={4257-65}
}
Exposure of Saccharomyces cerevisiae to sorbic acid strongly induces two plasma membrane proteins, one of which is identified in this study as the ATP-binding cassette (ABC) transporter Pdr12. In the absence of weak acid stress, yeast cells grown at pH 7.0 express extremely low Pdr12 levels. However, sorbate treatment causes a dramatic induction of Pdr12 in… CONTINUE READING