The pdm3 Locus Is a Hotspot for Recurrent Evolution of Female-Limited Color Dimorphism in Drosophila

  title={The pdm3 Locus Is a Hotspot for Recurrent Evolution of Female-Limited Color Dimorphism in Drosophila},
  author={Amir Yassin and Emily K Delaney and Adam J. Reddiex and Thaddeus D Seher and H{\'e}lo{\"i}se Bastide and Nicholas C. Appleton and Justin Lack and Jean R. David and Stephen F. Chenoweth and John E. Pool and Artyom Kopp},
  journal={Current Biology},

Figures from this paper

Divergent phenotypic plasticity of a convergent Mendelian trait in Drosophila
Analysis of the thermal plasticity of abdominal pigmentation in a third species, D. erecta, found that in spite of a low overall plasticity in monogenic species compared to D. melanogaster, the two monogenicspecies showed divergent plasticity patterns in respect to the response to temperature and to the degree of dominance in heterozygotes.
Evolution of a neuromuscular sexual dimorphism in the Drosophila montium species group
Compared the abdominal musculature of 41 Drosophila montium group species, to determine whether any of these species carry a male-specific muscle of Lawrence (MOL), quantitative analysis revealed that the size of a sexually dimorphic MOL analog found in 19 montia group species varied widely from species to species, suggesting the gradual evolution of this sexuallyDimorphic neuromuscular trait.
Evolution of assortative mating following selective introgression of pigmentation genes between two Drosophila species
Results indicate that selective introgression of as low as 0.5% of the genome can beget morphologically distinct and reproductively isolated strains, two prerequisites for the delimitation of new species.
An investigation of Y chromosome incorporations in 400 species of Drosophila and related genera
Y incorporation is an underappreciated mechanism affecting Y chromosome evolution; the results show that at least in Drosophila it plays a relevant role and highlight the need of similar studies in other groups.
Evolution of wing pigmentation in Drosophila: Diversity, physiological regulation, and cis‐regulatory evolution
  • S. Koshikawa
  • Biology
    Development, growth & differentiation
  • 2020
The process of wing formation in Drosophila, the general mechanism of pigmentation formation, and the transport of substances necessary for pigmentation, including melanin precursors, through wing veins are summarized here.
A Genomic Reference Panel for Drosophila serrata
Re-sequenced inbred lines of Drosophila serrata are described, sampled from a natural population situated deep within the species endemic distribution in Brisbane, Australia, and preliminary population genetic analyses revealed high nucleotide diversity and, on average, negative Tajima’s D values.
Convergent evolution of sex-specific leg ornaments in Drosophilidae – from cells to structures
It is shown that the sex brush has evolved independently at least three times from sexually monomorphic ancestral morphology, and all sex brushes have very similar fine structure and develop through indistinguishable cellular processes, providing a striking example of developmental convergence.
Widespread cis- and trans-regulatory evolution underlies the origin, diversification, and loss of a sexually dimorphic fruit fly pigmentation trait.
It is shown that the transgene host frequently determines CRE activity, implicating trans-evolution as a significant factor for this trait's diversity, and an amenability to change for the landscape of trans-regulators is suggested.
Phylogenomic analyses of the genus Drosophila reveals genomic signals of climate adaptation
It is concluded that adaptation to different climates in the genus Drosophila has been associated with large‐scale and multifaceted genomic changes.


Quantitative trait loci responsible for variation in sexually dimorphic traits in Drosophila melanogaster.
This report maps quantitative trait loci responsible for variation in sexually dimorphic traits (abdominal pigmentation and the number of ventral abdominal bristles and sex comb teeth) in a natural population of Drosophila melanogaster and demonstrates that multiple bab alleles that confer distinct phenotypes appear to segregate in natural populations at appreciable frequencies.
Recurrent Modification of a Conserved Cis-Regulatory Element Underlies Fruit Fly Pigmentation Diversity
These findings represent an example where the paths of evolution appear biased to a specific CRE, and drastic changes in function were accompanied by deep conservation of key regulatory linkages.
A Conserved Supergene Locus Controls Colour Pattern Diversity in Heliconius Butterflies
The results imply that a conserved yet relatively unconstrained mechanism underlying pattern switching can affect mimicry in radically different ways, and show that adaptive evolution, both convergent and diversifying, can occur by the repeated involvement of the same genomic regions.
Stepwise Modification of a Modular Enhancer Underlies Adaptation in a Drosophila Population
This work localized a suite of substitutions in a modular enhancer of the ebony locus responsible for adaptive melanism in a Ugandan Drosophila population, and underscores how enhancers are distinct macromolecular entities, subject to fundamentally different, and generally more relaxed, functional constraints relative to protein sequences.
Phenotypic plasticity of abdominal pigmentation in Drosophila kikkawai: multiple interactions between a major gene, sex, abdomen segment and growth temperature
In D. kikkawai, climatic adaptation might occur more by changing the frequency of the D allele than by phenotypic plasticity, and amount of change induced by different growth temperatures was variable according to genotype and segment.
Genetic mechanisms and constraints governing the evolution of correlated traits in drosophilid flies
It is shown that both evolutionary diversification and convergence can be due to evolution at the same locus, by comparing abdominal pigmentation and trichome patterns and the expression of Bric-à-brac2 (Bab2), which regulates both traits in D. melanogaster.
Ancient balancing selection at tan underlies female colour dimorphism in Drosophila erecta
A striking signal of ancient balancing selection is found at the ‘male-specific enhancer' of tan, with exceptionally high sequence divergence between light and dark alleles, suggesting that this dimorphism has been adaptively maintained for millions of years.
Chromosomal rearrangements maintain a polymorphic supergene controlling butterfly mimicry
The results indicate that allelic combinations at known wing-patterning loci have become locked together in a polymorphic rearrangement at the P locus, forming a supergene that acts as a simple switch between complex adaptive phenotypes found in sympatry.