The paxillin LD motifs.

@article{Tumbarello2002ThePL,
  title={The paxillin LD motifs.},
  author={David A Tumbarello and Michael C. Brown and Christopher E Turner},
  journal={FEBS letters},
  year={2002},
  volume={513 1},
  pages={
          114-8
        }
}
Adapter/scaffold proteins, through their multidomain structure, perform a fundamental role in facilitating signal transduction within cells. Paxillin is a focal adhesion adapter protein implicated in growth factor- as well as integrin-mediated signaling pathways. The amino-terminus of paxillin contains five leucine-rich sequences termed LD motifs. These paxillin LD motifs are highly conserved between species as well as within the paxillin superfamily. They mediate interactions with several… CONTINUE READING

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