The patterns of melanosome distribution in keratinocytes of human skin as one determining factor of skin colour

  title={The patterns of melanosome distribution in keratinocytes of human skin as one determining factor of skin colour},
  author={Haw-Yueh Thong and Shiou-Hwa Jee and C.-C. Sun and Raymond E. Boissy},
  journal={British Journal of Dermatology},
Background  One determining factor of skin colour is the distribution pattern of melanosomes within keratinocytes. Melanosomes in keratinocytes of light skin as in Caucasians are distributed as membrane‐bound clusters, whereas the melanosomes in keratinocytes of dark skin as in African/American individuals tend to be larger and distributed individually. It has been shown that melanin content, melanin composition and the size of melanosomes in the human epidermis vary considerably with both… 
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