The pattern of prion-related protein expression in the gastrointestinal tract

@article{Pammer2000ThePO,
  title={The pattern of prion-related protein expression in the gastrointestinal tract},
  author={Johannes Pammer and Heide S. Cross and Yveline Frobert and Erwin Tschachler and Georg Oberhuber},
  journal={Virchows Archiv},
  year={2000},
  volume={436},
  pages={466-472}
}
Prion diseases or transmissible spongiform encephalopathies have been shown to be communicated by oral ingestion of the infectious agent. However, the exact route of transmission is still unknown. In order to better understand the pathophysiology of these diseases, it is crucial to identify cell types of peripheral tissues in which the infectious agent may propagate. Since expression of cellular prion protein (PrPc) is a prerequisite for prion replication, we determined the expression of PrPc… CONTINUE READING
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Distri - bution and submicroscopic immunogold localization of cellular prion protein ( PrPc ) in extracerebral tissues

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