The pattern of monocyte recruitment in tumors is modulated by MCP-1 expression and influences the rate of tumor growth.

@article{Zhang1997ThePO,
  title={The pattern of monocyte recruitment in tumors is modulated by MCP-1 expression and influences the rate of tumor growth.},
  author={Lanjing Zhang and Ali Hosseini Khayat and Han Cheng and Dana T Graves},
  journal={Laboratory investigation; a journal of technical methods and pathology},
  year={1997},
  volume={76 4},
  pages={579-90}
}
Macrophage infiltration is an important aspect of the host response to tumor growth. Tumor-associated macrophages often exhibit intratumoral or peritumoral infiltration patterns. However, the mechanism that mediates distinctive patterns of macrophage infiltration and their impact on tumor growth is not known. We studied macrophage infiltration and the effect of this infiltration on tumor growth in mice inoculated with four human tumor cell lines. We report here that tumor cells producing high… CONTINUE READING

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