The pattern of inflammatory/anti-inflammatory cytokines and chemokines in type 1 diabetic patients over time

  title={The pattern of inflammatory/anti-inflammatory cytokines and chemokines in type 1 diabetic patients over time},
  author={A. Chatzigeorgiou and Vaggelis Harokopos and Christina Mylona-Karagianni and E. Tsouvalas and V. Aidinis and E. Kamper},
  journal={Annals of Medicine},
  pages={426 - 438}
  • A. Chatzigeorgiou, Vaggelis Harokopos, +3 authors E. Kamper
  • Published 2010
  • Medicine
  • Annals of Medicine
  • Abstract Aims. To evaluate the profile of pro- and anti-inflammatory cytokines in type 1 diabetes mellitus (T1DM) and the way they are connected in co-regulated networks and determine whether disease duration influences their pattern. Methods. Plasma levels of 20 cytokines and soluble CD40 (sCD40) from 44 uncomplicated patients and 22 healthy controls (HCs) were measured using enzyme-linked immunosorbent assay (ELISA) and protein array technology. Results. Patients showed significantly higher… CONTINUE READING
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