The pattern of function-related regional cerebral blood flow investigated by single photon emission tomography with 99mTc-HMPAO in patients with presenile Alzheimer's disease and Korsakoff's psychosis.

@article{Hunter1989ThePO,
  title={The pattern of function-related regional cerebral blood flow investigated by single photon emission tomography with 99mTc-HMPAO in patients with presenile Alzheimer's disease and Korsakoff's psychosis.},
  author={Richard Hunter and R McLuskie and David Wyper and James Patterson and J. E. Christie and Durryle N. Brooks and J Mcculloch and George Fink and Guy M. Goodwin},
  journal={Psychological medicine},
  year={1989},
  volume={19 4},
  pages={847-55}
}
Single photon emission tomography (SPET) with the lipophilic blood flow marker 99mTc-hexamethyl propyleneamine oxime (99mTc-HMPAO) has been used to determine regional uptake of radiolabel into brain regions of patients with presenile Alzheimer's disease and Korsakoff's psychosis, and age-matched controls. Using occipital cortical uptake as reference area, the pattern of relative regional cerebral blood flow (rCBF) was determined in other cortical areas and basal ganglia. In Alzheimer's disease… CONTINUE READING
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