The pathways to tumor suppression via route p38.

Abstract

Besides its well-known functions in inflammation and other stresses, the p38 mitogen-activated protein kinase pathway also negatively regulates cell proliferation and tumorigenesis. Inactivation of the p38 pathway enhances cellular transformation and renders mice prone to tumor development with concurrent disruption of the induction of senescence… (More)

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Cite this paper

@article{Han2007ThePT, title={The pathways to tumor suppression via route p38.}, author={Jiahuai Han and Peiqing Sun}, journal={Trends in biochemical sciences}, year={2007}, volume={32 8}, pages={364-71} }