The pathway of secretion of proteinases in Trichomonas vaginalis.

  title={The pathway of secretion of proteinases in Trichomonas vaginalis.},
  author={David J. Scott and M J North and Graham H. Coombs},
  journal={International journal for parasitology},
  volume={25 6},
Trichomonads secrete large amounts of hydrolytic enzymes into liquid growth medium. Proteinase release by Trichomonas vaginalis has been quantified after resuspension of the parasite in a simple buffered maltose medium. After 6 h incubation, 70-90% of each of two cysteine proteinase activities, one towards benzyloxycarbonyl-arginyl-arginine 4-nitroanilide (Z-RR-Nan) and the other active towards N-benzoyl-prolyl-phenylalanyl-arginine 4-nitroanilide (Bz-PFR-Nan), was extracellular. This release… CONTINUE READING