The pathway of miRNA maturation.

  title={The pathway of miRNA maturation.},
  author={Michael Sand},
  journal={Methods in molecular biology},
MicroRNAs (miRNAs) are a novel class of 17-23 nucleotide short, nonprotein-coding RNA molecules which have emerged to be key players in posttranscriptional gene regulation. In this chapter we give an in-depth review of the classic, canonical mammalian miRNA maturation pathway and discuss new, noncanonical alternatives such as the mirtron pathway which were recently described. 

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