The pathophysiology of propofol infusion syndrome: a simple name for a complex syndrome

@article{Vasile2003ThePO,
  title={The pathophysiology of propofol infusion syndrome: a simple name for a complex syndrome},
  author={B. Vasile and F. Rasulo and A. Candiani and N. Latronico},
  journal={Intensive Care Medicine},
  year={2003},
  volume={29},
  pages={1417-1425}
}
  • B. Vasile, F. Rasulo, +1 author N. Latronico
  • Published 2003
  • Medicine
  • Intensive Care Medicine
  • Propofol infusion syndrome (PRIS) is a rare and often fatal syndrome described in critically ill children undergoing long-term propofol infusion at high doses. Recently several cases have been reported in adults, too. The main features of the syndrome consist of cardiac failure, rhabdomyolysis, severe metabolic acidosis and renal failure. To date 21 paediatric cases and 14 adult cases have been described. These latter were mostly patients with acute neurological illnesses or acute inflammatory… CONTINUE READING

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