The pathology of viral hepatitis types A and B in chimpanzees. A comparison.

@article{Dienstag1976ThePO,
  title={The pathology of viral hepatitis types A and B in chimpanzees. A comparison.},
  author={Jules L. Dienstag and Hans Philipp Popper and RobertH. Purcell},
  journal={The American journal of pathology},
  year={1976},
  volume={85 1},
  pages={
          131-48
        }
}
The histologic manifestations in the livers of chimpanzees inoculated with hepatitis A and B virus were compared with each other and correlated with biochemical, serologic, and virologic observations. Both types of hepatitis reveal alterations similar to those seen in human hepatitis, but the lesions--particularly the hepatocellular necrosis--are far milder. Hepatitis Type A in chimpanzees is a disease of short incubation period and duration. The hepatocytic alterations are mainly restricted to… CONTINUE READING

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