The pathology of feline GM2 gangliosidosis.

@article{Cork1978ThePO,
  title={The pathology of feline GM2 gangliosidosis.},
  author={Linda Collins Cork and John F. Munnell and Michael D Lorenz},
  journal={The American journal of pathology},
  year={1978},
  volume={90 3},
  pages={723-34}
}
An 11-week-old and a 6-month-old kitten with feline GM2 gangliosidosis and deficiency in both A and B isoenzymes of beta-D-N-acetyl hexosaminidase were studied by light transmission (TEM), and scanning electron microscopy (SEM). Neurons throughout the nervous system contained cytoplasmic, membrane-bound inclusions which were PAS-positive at the fine structure level these inclusions were composed of membranous arrays in whorls, vesicles, or multilaminated stacks. Fusion of the bounding membranes… CONTINUE READING

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