The pathology of cholestasis.

  title={The pathology of cholestasis.},
  author={Melissa K Li and James M. Crawford},
  journal={Seminars in liver disease},
  volume={24 1},
Hepatic formation of bile is critical to survival and is one of the most easily disrupted liver functions. Liver biopsy is performed to obtain a definitive diagnosis of cause, to exclude potential etiologies, or simply to assist in development of a differential diagnosis. Parenchymal changes of cholestasis (feathery degeneration of hepatocytes, dilated bile canaliculi with retained bile, Kupffer cell phagocytosis of bile that has leaked into the sinusoidal space) are nonspecific and may be seen… CONTINUE READING


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