The pathology and molecular biology of anal intraepithelial neoplasia: comparisons with cervical and vulvar intraepithelial carcinoma

@article{Zbar2001ThePA,
  title={The pathology and molecular biology of anal intraepithelial neoplasia: comparisons with cervical and vulvar intraepithelial carcinoma},
  author={Ariella Zbar and Claus Fenger and Jonathan Efron and Marc Beer-Gabel and Steven D. Wexner},
  journal={International Journal of Colorectal Disease},
  year={2001},
  volume={17},
  pages={203-215}
}
Background: Anal intraepithelial neoplasia (AIN) is a well-described pathological precursor of invasive squamous cell carcinoma which has recently been detected with increasing frequency in immunocompromised patients, particularly those with seropositivity for human immunodeficiency virus (HIV). The epidemiology and natural history of this entity is somewhat unclear, since the overall prevalence in the HIV seronegative population is unknown. Discussion: There is a clear etiological association… CONTINUE READING

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