The pathogenic 16/6 idiotype in patients with silica associated systemic lupus erythematosus (SLE) and uranium miners with increased risk for development of SLE.

@article{Conrad1998TheP1,
  title={The pathogenic 16/6 idiotype in patients with silica associated systemic lupus erythematosus (SLE) and uranium miners with increased risk for development of SLE.},
  author={Karsten Conrad and Yair M Levy and Miri Blank and Juergen Mehlhorn and K H Frank and Beate Roch and Yehuda Shoenfeld},
  journal={The Journal of rheumatology},
  year={1998},
  volume={25 4},
  pages={660-6}
}
OBJECTIVE To investigate the prevalence of the 16/6 idiotype (16/6 Id), a major cross reactive idiotype of anti-DNA antibodies involved in the pathogenesis of experimental lupus, in subjects with an exogenous risk for the development of systemic lupus erythematosus (SLE). METHODS The titer of 16/6 Id was determined by ELISA in sera of uranium miners… CONTINUE READING