The past and present role of the Sabin-Feldman dye test in the serodiagnosis of toxoplasmosis.

@article{ReiterOwona1999ThePA,
  title={The past and present role of the Sabin-Feldman dye test in the serodiagnosis of toxoplasmosis.},
  author={Ingrid Reiter-Owona and E P Petersen and David H M Joynson and Horst Asp{\"o}ck and Marie Laure Dard{\'e} and Ruediger Disko and O Dreazen and Henri Dumon and Raffaella Grillo and Uwe Gross and Michael Hayde and Richard Holliman and Darrel O Ho-Yen and Klaus Janitschke and P{\aa}l Arne Jenum and Kamal Naser and Mitch Olszewski and Philippe Thulliez and Hanns Martin Seitz},
  journal={Bulletin of the World Health Organization},
  year={1999},
  volume={77 11},
  pages={929-35}
}
The dye test for the detection of Toxoplasma-specific antibodies was first described by Sabin and Feldman 50 years ago. The test is highly specific and sensitive and considerable information is available on the development and persistence of dye test antibodies after primary Toxoplasma infection. However, the test uses live Toxoplasma gondii and is now only employed in a few laboratories. It is still the reference method for the serodiagnosis of toxoplasmosis, and a multicentre study comparing… CONTINUE READING