The paralyzing effect of midazolam on Onchocerca volvulus microfilariae in vitro.

@article{LaukammJosten1987ThePE,
  title={The paralyzing effect of midazolam on Onchocerca volvulus microfilariae in vitro.},
  author={U Laukamm-Josten},
  journal={The American journal of tropical medicine and hygiene},
  year={1987},
  volume={37 1},
  pages={152-6}
}
  • U Laukamm-Josten
  • Published 1987 in
    The American journal of tropical medicine and…
Midazolam, a water soluble benzodiazepine derivative, inhibited the motility of Onchocerca volvulus microfilariae in vitro at concentrations of 25, 50, and 100 micrograms/ml. The effect was proportional to the concentrations used. Microfilariae regained motility after elimination of midazolam by washing. Diethylcarbamazine did not alter the midazolam effect… CONTINUE READING