The pancreatic beta-cell in the islet and organ community.

  title={The pancreatic beta-cell in the islet and organ community.},
  author={Daniel Eberhard and Eckhard Lammert},
  journal={Current opinion in genetics & development},
  volume={19 5},
The endocrine pancreas consists of highly vascularized and innervated endocrine mini-organs--the islets of Langerhans. These contain multiple types of hormone-producing cells, including the insulin-secreting beta-cell. The major task of the fully differentiated beta-cell is the tight regulation of blood glucose levels by secreting insulin into the blood stream. This requires molecular features to measure glucose and produce, process, and release insulin by exocytosis. Now multiple interactions… CONTINUE READING

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