The pancreatic beta-cell as a fuel sensor: an electrophysiologist's viewpoint

@article{Rorsman1997ThePB,
  title={The pancreatic beta-cell as a fuel sensor: an electrophysiologist's viewpoint},
  author={Patrik Rorsman},
  journal={Diabetologia},
  year={1997},
  volume={40},
  pages={487-495}
}
The pancreatic beta cell serves as the fuel sensor of the entire body and controls, via secretion of the hypoglycaemic hormone insulin, the blood glucose concentrations within narrow limits by regulation of glucose uptake and release. During the last 30 years, a combination of biochemical and ultrastructural approaches has resulted in dramatic progress in the understanding of the processes by which glucose and other nutrients modulate the release of insulin. The beta cells have also been… CONTINUE READING
Highly Cited
This paper has 202 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 117 extracted citations

Imaging dynamic insulin release using a fluorescent zinc indicator for monitoring induced exocytotic release (ZIMIR).

Proceedings of the National Academy of Sciences of the United States of America • 2011
View 14 Excerpts
Highly Influenced

203 Citations

01020'98'03'09'15
Citations per Year
Semantic Scholar estimates that this publication has 203 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
Showing 1-10 of 57 references

Mutations of the sulfonylurea receptor gene in familial persistent hyperinsulinemic hypoglycemia

PM Thomas, GJ Cote, N Wohlik
of infancy. Science • 1995
View 6 Excerpts
Highly Influenced

Ultrastructural morphometry of the pancreatic β-cell

Diabetologia • 1973
View 3 Excerpts
Highly Influenced