The pancreatic beta-cell as a fuel sensor: an electrophysiologist's viewpoint

  title={The pancreatic beta-cell as a fuel sensor: an electrophysiologist's viewpoint},
  author={Patrik Rorsman},
The pancreatic beta cell serves as the fuel sensor of the entire body and controls, via secretion of the hypoglycaemic hormone insulin, the blood glucose concentrations within narrow limits by regulation of glucose uptake and release. During the last 30 years, a combination of biochemical and ultrastructural approaches has resulted in dramatic progress in the understanding of the processes by which glucose and other nutrients modulate the release of insulin. The beta cells have also been… CONTINUE READING
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