The pancreas in familial adenomatous polyposis.

  title={The pancreas in familial adenomatous polyposis.},
  author={Alaa Elkharwily and Klaus Gottlieb},
  journal={JOP : Journal of the pancreas},
  volume={9 1},
Familial adenomatous polyposis is an archetypal disease illustrating the genetic basis of human cancer. The adenomatous polyposis coli gene functions as a tumor suppressor with hundreds of known mutations that result in a defective adenomatous polyposis coli protein. In addition to the certain fate of colon cancer without colectomy, patients with familial… CONTINUE READING