The pancreas as a source of cardiovascular cell activating factors.

  title={The pancreas as a source of cardiovascular cell activating factors.},
  author={Erik B Kistler and Tony E. Hugli and Geert W Schmid-Sch{\"o}nbein},
  volume={7 3},
OBJECTIVE Physiological shock leads to elevated levels of plasma factors that activate circulating leukocytes and endothelial cells, thereby compromising microvascular functions. The nature and source of these plasma-derived activators are unknown. To examine the possible origin of these factors, we homogenized rat internal organs and measured their activity on cardiovascular cells in vivo and in vitro. METHODS Fresh tissue samples from small intestine, spleen, heart, liver, kidney, adrenals… CONTINUE READING


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