The pab1 gene of Coprinus cinereus encodes a bifunctional protein for para-aminobenzoic acid (PABA) synthesis: implications for the evolution of fused PABA synthases.

Abstract

The pab1 gene of the basidiomycete Coprinus cinereus encodes PABA synthase, necessary for para-aminobenzoic acid production. The C. cinereus protein is bifunctional with an N-terminal glutamine amidotransferase domain and a C-terminal chorismate amination domain. In most bacteria, these two functions are encoded in separate genes (e.g., pabA and pabB of E… (More)

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@article{James2002ThePG, title={The pab1 gene of Coprinus cinereus encodes a bifunctional protein for para-aminobenzoic acid (PABA) synthesis: implications for the evolution of fused PABA synthases.}, author={Timothy Y James and Robert P Boulianne and Alan P F Bottoli and Jos{\'e} David Granado and Markus Aebi and Ursula K{\"u}es}, journal={Journal of basic microbiology}, year={2002}, volume={42 2}, pages={91-103} }