The pH of the Skin Surface and Its Impact on the Barrier Function

  title={The pH of the Skin Surface and Its Impact on the Barrier Function},
  author={M.-H. Schmid-Wendtner and Hans Christian Korting},
  journal={Skin Pharmacology and Physiology},
  pages={296 - 302}
The ‘acid mantle’ of the stratum corneum seems to be important for both permeability barrier formation and cutaneous antimicrobial defense. However, the origin of the acidic pH, measurable on the skin surface, remains conjectural. Passive and active influencing factors have been proposed, e.g. eccrine and sebaceous secretions as well as proton pumps. In recent years, numerous investigations have been published focusing on the changes in the pH of the deeper layers of the stratum corneum, as… 

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